IL-1β and IL-8 influence on cytoprotective mechanisms in liver tissue in morbid obesity patients with comorbidities
... factor contributing to the development of NAFLD and type 2 diabetes in morbid obesity is the disruption of the function of systems that maintain redox balance by suppressing the production of the factors NRF2, TFAM, AMPK, HSF1, HSP70 in liver tissue.
Vulf M.A., Kuznetsov G.L., Komar A.A., Safiullina L.A., Karpeeva E.N., Shunkina D.A., Bograya M.M., Gazatova N.D., Kirienkova E.V., Litvinova L.S.
NAFLD, type 2 diabetes, cytoprotection, mitochondria, cytokines
108-120